Phentermine (Adipex) is an effective and popular weight loss drug in the United States.
Phentermine is indicated as a short-term (up to several weeks) weight loss supplement in an exercise-based, behavior modification, and caloric restriction regimen for the treatment of exogenous obesity in patients with an initial body mass index greater than or equal to 30 kg/m2.
The dosage must be individualized to respond appropriately with the lowest effective dose.
The usual dose for adults is one capsule (37.5 mg) per day, as prescribed by the physician, which is given to control appetite before breakfast or 1-2 hours after breakfast.
The usual dose for adults is one tablet (37.5 mg) per day, as prescribed by the doctor, before breakfast or 1-2 hours after breakfast. The dosage may be adjusted for the patient. In some patients, half a tablet (18.75 mg) may be sufficient daily, while in some cases, half a tablet (18.75 mg) twice daily may be desirable.
Phentermine® is not recommended for use in children under 16 years of age.
Avoid using the drug in the late evening because of possible insomnia.
You can buy Phentermine online or in your local drugstore if you have a valid medical prescription from your doctor.
Some dealers from abroad offer phentermine without a prescription and even ship it to the US. However, doctors and other experts advise against taking advantage of such offers.
No, you cannot buy Phentermine without a prescription in the US or Canada. Moreover, it is a controlled substance, and misuse can lead to abuse. That is why only your doctor can issue you a prescription.
However, you can always buy Phentermine (or generic Adipex) online from some offshore pharmacies. They sell drugs without a prescription, which may be legal abroad, but not in the US.
Usually, these pharmacies offer various payment methods like Visa, MasterCard, Paypal, and even Bitcoin. It is up to you to decide whether you want to risk and order generic Phentermine without a prescription from such websites. Beware of the possibility of getting fake or low-quality drugs.
Dosages for Phentermine vary by form and concentration.
Until 2016, variants containing 15 mg, 30 mg and 37.5 mg of the active ingredient were available. In 2016, an additional 8 mg variant was approved that can be taken up to three times daily. However, the last dose should not be taken too late in the evening to avoid sleep disturbances.
Avoid using the drug in cases of:
Phentermine® is indicated only as a short-term (several weeks) treatment for exogenous obesity. The safety and effectiveness of combination therapy with Phentermine® and other weight loss medications, including prescription drugs, over-the-counter medicines, and herbal products, have not been found.
Hence, coadministration of Phenermin® and these drugs are not recommended.
If tolerance to the drug develops, the recommended dose should not be exceeded to increase the effect. Instead, the drug should be discontinued.
Effects on ability to perform potentially hazardous tasks
Phentermine® may affect the patient’s ability to perform potentially dangerous activities, such as operating machinery or driving.
Phentermine® is chemically and pharmacologically related to amphetamine and other stimulants that have been largely misused. The potential for misuse of Phentermin® should be considered when evaluating the desirability of taking the drug as part of a weight loss program.
Concomitant use of alcohol with phentermine® may result in an adverse drug reaction.
Beware of prescribing phentermine® for patients with mild hypertension (risk of high blood pressure).
Phentermine® is contraindicated during pregnancy because weight loss offers no potential benefit to the pregnant woman and may result in fetal damage. Minimal weight gain and weight loss are recommended for all pregnant women, including those who are already overweight or obese, because of the mandatory weight gain in maternal tissue during pregnancy.
In general, dose selection for the elderly patient should be cautious, usually starting at the lower end of the dose range, reflecting the increased frequency of reduced liver, kidney, or heart function, as well as comorbid disease or other drug therapy.
This medication is known to be excreted primarily through the kidneys, and the risk of toxic reactions to this medication may be higher in patients with renal insufficiency. Since elderly patients are more likely to have reduced renal function, caution should be exercised in dose selection, and it may be helpful to monitor renal function.
The following side effects are the most common during drug use:
Primary pulmonary hypertension and/or heart valve disease belching, palpitations, tachycardia, and increased blood pressure.
Excessiveness, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis.
Dry mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disorders.
Impotence, changes in libido
Manifestations of acute overdose include restlessness, tremors, rapid breathing, confusion, assertiveness, hallucinations, and panic. Fatigue and depression usually result in central stimulation. Cardiovascular effects include tachycardia, arrhythmia, high blood pressure or hypotension, and circulatory. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps.
An overdose of pharmacologically similar compounds has resulted in fatal poisoning, seizures, and coma.
If you experience some or all symptoms mentioned above, seek immediate medical help.